Community-based tuberculosis triage testing for hard-to-reach populations in Southern Africa
“Finding the missing TB cases”
Worldwide, only 2/3 of the new TB cases are currently notified to national authorities and reported to WHO.
(WHO report 2019)
TB TRIAGE+ at a glance
Tuberculosis is a poverty-related disease which particularly affects vulnerable and underserved populations. The World Health Organization has developed target product profiles for community-based TB triage testing. CAD4TB, an extensively validated digital chest x-ray analysis platform using deep-learning technology, and a blood test for C-reactive protein, which is a marker of inflammation or infection, are two very promising diagnostic tools which have the potential to meet the targets for TB triage.
The 4-year African-European TB TRIAGE+ project is funded by the European and Developing Countries Clinical Trials Partnership (EDCTP) and will assess the accuracy, impact and cost-effectiveness of CAD4TB and C-reactive protein as triage tools for community-based TB screening in rural and semi-rural Lesotho and KwaZulu-Natal, South Africa.